Processing Of Sensory Information In The Superficial Dorsal Horn Of The Spinal Cord

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As such, contributions across the whole field of biotechnology were planned and the present volume represents perspectives from specialists in different areas.This book is the proceedings of a NATO Advanced Studies Institute organized jointly by LNETI, the National Laboratories of the Ministry of Industry of the Portuguese Government and The Institute for Biotechnological Studies in the UK. Perspectives in Biotechnology Biotechnology has been defined in a recent OECD publication as "the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services" and the contents of this book, which often describe research from interdisciplinary groups, reflect this title.

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This volume addresses some facets of the adverse actions of chemical agents on the central and peripheral nervous systems in developing and mature states. Others disrupt sites required for the maintenance of cellular integrity, and these variably result in degenerative responses of neurons and myelinating cells.. Is the chemical a single or multiple entity; is it metabolized; how does it gain access to neural tissue? Some of the effects of these chemicals are short-lasting and rapidly reversible; others, especially those that cause structural damage to the nervous system, may result in permanent damage to the organism.

The nervous system has several levels of vulnerability to toxic substances. Recent Advances in Nervous System Toxicology Some substances perturb ion channels or synaptic mechanisms required for the orderly transfer of electrochemical information within the nervous system. Is the chemical a single or multiple entity; is it metabolized; how does it gain access to neural tissue? Some of the effects of these chemicals are short-lasting and rapidly reversible; others, especially those that cause structural damage to the nervous system, may result in permanent damage to the organism. Further sites of vulnerability include the delicate neural vasculature and neurohumeral mechanisms responsible for physiological homeostasis.